Afriplex Corac-Q™ – A Natural Alternative for Respiratory Health
With the development of Afriplex Corac-Q™, Afriplex succeeded in pioneering another game-changer ingredient in the pharmaceutical space. Using the latest extraction technology, this API (Active Pharmaceutical Ingredient) is designed to promote respiratory health and assist in the prevention of viral infection.
Afriplex Corac-Q™ is a unique plant-based ingredient, developed by standardising pre-selected components and thereby ensuring enhanced efficacy when formulated in medicines destined for bronchial health.
The API’s active components, namely Aspalathin, Quercetin, Zinc and Vitamin D, enjoy the support of scientifically backed research in the arena of respiratory health and anti-viral activity.
In combination, these components may exert antiviral and immune stimulating effects, thereby assisting in immune function and health.
SARS-CoV-2: A Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as Covid-19, typically enters the body through the mouth or nose, after which the virus is transported to the lung’s alveoli (air sacs).
- The spike protein on the virion binds to the cell-surface protein ACE2. The TMPRSS2 enzyme assists the virion to enter the host cell.
- The virion releases its RNA.
- Some of the RNA is translated into proteins by the host cell’s machinery.
- Some of these proteins form a replication complex to produce more RNA.
- Proteins and RNA are assembled to form a new virion. This process takes place in the Golgi of the host cell.
- The virion is released from the cell.
When considering mechanisms of protecting the body against the SARS-CoV-2 infection, infection may be prevented by limiting the spike protein from binding to the cellular surface of the host cell or by deactivating enzymes required during the initial stages of infection.
Another mechanism would be to eliminate or decrease the rate of virion replication within the host cell, thereby preventing Covid-19 onset.
The anti-viral effect of the extract of Rooibos (Aspalathus linearis) is well documented and in addition has been proven to interfere with the virus replication process. While Rooibos is also known for its bronchodilatory effect, its unique antioxidant, Aspalathin, has been associated with anti-inflammatory and immune function modulation properties.
The extract of unfermented Rooibos contains Quercetin and its associated variants like iso-quercetin. Quercetin is a widely distributed plant flavonoid with antioxidant properties, found in various fruits, berries and teas. After the outbreak of the SARS epidemic, Quercetin has been identified as one of the possible therapies for combating Covid-19. While some research has confirmed a positive effect in treating upper respiratory tract infection, other studies indicate that quercetin exhibit efficacy as prophylactic as well as treatment for this disease.
Zinc has been proven to possess antiviral effects. Multiple antiviral effects of Zn2+ have been demonstrated in a variety of viral species, including several nidoviruses, to which SARS-CoV-2 belongs. It suggests that Zinc supplementation may be of benefit for prophylaxis and treatment of Covid-19. Another study suggests that increased intracellular Zn2+ concentrations have the potential to combat corona virus strains by interfering with the replication mechanism of the virion.
Recent studies have found that sufficient levels of Vitamin D may lower the likelihood of developing respiratory infections associated with colds and influenza. Experts propose that low Vitamin D levels may hamper the immune system and that sufficient levels of Vitamin D reduces the risk of viral infection.
For a detailed description of Afriplex Corac-Q™, its mechanism and associated research, feel free to visit www.coracq.com.